カワムラ　クニオ   KAWAMURA Kunio   川村　邦男    所属   広島修道大学  人間環境学部    職種   教授
言語種別	英語
発行・発表の年月	2022/10
形態種別	学術論文
査読	査読有り
標題	Life on minerals: Binding behaviors of oligonucleotides on zirconium silicate and its inhibitory activity for the self-cleavage of hammerhead ribozyme
執筆形態	共著
掲載誌名	Life
掲載区分	国外
出版社・発行元	MDPI
巻・号・頁	12,pp.1689
頁数	16
担当範囲	Corresponding author
著者・共著者	Kunio Kawamura, Jean-François Lambert, Louis M. P. Ter-Ovanessian, Jacques Vergne, Guy Hervé, Marie-Christine Maurel
概要	The role of minerals in the chemical evolution of RNA molecules is an important issue when considering the early stage of the Hadean Earth. In particular, the interaction between functional ribozymes and ancient minerals under simulated primitive conditions is a recent research focus. We are currently attempting to design a primitive RNA metabolic network which would function with minerals, and believe that the simulated chemical network of RNA molecules would be useful for evaluation of the chemical evolution from a simple RNA mixture to an RNA-based life-like system. The present study suggests that the chemical evolution of functional RNA molecules requires specific conformational binding, resulting in efficient ribozyme function as well as zirconium silicate for the chemical evolution of biomolecules.