カワムラ　クニオ   KAWAMURA Kunio   川村　邦男    所属   広島修道大学  人間環境学部    職種   教授
言語種別	英語
発行・発表の年月	2009/12
形態種別	その他の研究業績
標題	Oligopeptide formation under hydrothermal conditions using a micro-flow hydrothermal reactor,
執筆形態	共著
掲載誌名	Origins Life Evol. Biospheres
掲載区分	国外
出版社・発行元	ISSOL
巻・号・頁	39,pp.203-204
担当範囲	Corresponding author
著者・共著者	◎Kunio Kawamura, Hitoshi Takeya, Ai Akiyoshi, Masanori Shimahashi
概要	We have established a hydrothermal micro-flow reactor system (HFR), which enables monitoring hydrothermal reactions within 0.002 – 180 s at temperatures up to 400 °C. Here we show details and further investigations concerning these reactions. First, during the degradation of L-alanyl-L-alanyl-L-alanyl-L-alanine ((Ala)4) under hydrothermal conditions, (Ala)5 was detected. Second, the formation of oligopeptide-like molecules of length up to 20-mers proceeded from L-glutamic acid (Glu) and L-aspartic acid (Asp). Yields of up to 0.17–0.57% were obtained in an acidic solution within 13 - 183 s at 250–310 ºC. The oligopeptide-like molecules were assigned as pyroglutamic acid-capped Asp oligopeptides with linear and/or branched linkages. During the elongations, DKP isomers were not detected.