カワムラ　クニオ   KAWAMURA Kunio   川村　邦男    所属   広島修道大学  人間環境学部    職種   教授
言語種別	英語
発行・発表の年月	1998/10
形態種別	学術論文
査読	査読有り
標題	Capillary electrophoretic separation of mono and dinucleotides of adenosine using cyclodextrin solutions with MgCl2 additive
執筆形態	単著
掲載誌名	J. Chromatography A
掲載区分	国外
巻・号・頁	802(1),pp.167-177
概要	The capillary electrophoretic separation of adenine, adenosine and nucleotide isomers of adenosine has been studied using several kinds of buffer solutions with cyclodextrin and metal additives in the presence and absence of sodium dodecyl sulfate. Optimum resolution of 2′,5′- and 3′,5′-adenylyladenosine monophosphate was obtained using β-cyclodextrin solution containing 10−4 M MgCl2. The mixture of adenine, adenosine and nine types of adenosine nucleotide was able to be separated simultaneously within 15 min under the optimum conditions. The method was applicable to the analysis of the simulation reaction for the prebiotic formation of adenosine nucleotides.