カワムラ　クニオ   KAWAMURA Kunio   川村　邦男    所属   広島修道大学  人間環境学部    職種   教授
言語種別	英語
発行・発表の年月	2000/08
形態種別	学術論文
査読	査読有り
標題	Monitoring hydrothermal reactions on the millisecond time scale using a micro-tube flow reactor and kinetics of ATP hydrolysis for the RNA world hypothesis
執筆形態	単著
掲載誌名	Bull. Chem. Soc. Jpn.
掲載区分	国内
巻・号・頁	73(8),pp.1805-1811
概要	A new method for monitoring hydrothermal reactions on the millisecond time scale has been developed using a micro-tube flow reactor. The system was designed based on a high-pressure pump, a sample-loop injector, a narrow-bore size capillary, a cooling bath, back-pressure tubing, and a sampling port. Kinetic analyses of the hydrolyses of adenosine 5′–triphosphate (ATP) and adenosine 5′–monophosphate (AMP) on the millisecond time range at 250—315 °C were demonstrated so as to evaluate the performance of the method. In conclusion, monitoring was successful for the hydrolysis of ATP and AMP in 2—50 ms using fused-silica capillary tubing with 0.015 and 0.025 mm inner diameter (ID). The method enables real-time monitoring of hydrothermal reactions in about 100-times shorter time range than other techniques.