カワムラ　クニオ   KAWAMURA Kunio   川村　邦男    所属   広島修道大学  人間環境学部    職種   教授
言語種別	英語
発行・発表の年月	2001/04
形態種別	学術論文
査読	査読有り
標題	Kinetics of the racemization of amino acids at 225 - 275 oC using a real-time monitoring method of hydrothermal reactions
執筆形態	共著
掲載誌名	Themchim. Acta
掲載区分	国外
巻・号・頁	375(1-2),pp.9-16
担当範囲	Corresponding anthor
著者・共著者	◎Kunio Kawamura, Masaru Yukioka
概要	The monitoring method of rapid hydrothermal reactions was successfully applied to the racemization of amino acids at 225±275oC. The rate constants of racemization of alanine, leucine, and phenylalanine were determined and the apparent activation energy was 124 kJ mol-1 for alanine, 120 kJ mol-1 for leucine, and 115 kJ mol-1 for phenylalanine, which are in good agreement with previous data at lower temperatures. In the course of the study, the observation of the formation of alanine anhydride, which is not possible by the conventional batch method, has been succeeded. Further, the cyclization of L-alanyl-L-alanine was possible to be monitored and it was confirmed that the reaction was much faster than racemization of alanine. Basing on the kinetic investigations, the importance of the racemization of amino acids is discussed from the viewpoint of the hydrothermal origin of life.