カワムラ　クニオ   KAWAMURA Kunio   川村　邦男    所属   広島修道大学  人間環境学部    職種   教授
言語種別	英語
発行・発表の年月	2001/11
形態種別	学術論文
査読	査読有り
標題	Hydrolytic stability of ribose phosphodiester bonds within several oligonucleotides at high temperatures using a real-time monitoring method for hydrothermal reactions
執筆形態	単著
掲載誌名	Chem. Lett.
掲載区分	国内
巻・号・頁	30(11),pp.1120-1121
概要	The hydrolytic stability of ribose phosphodiester bond within several types of oligonucleotides was measured at 150– 200 °C using a real-time monitoring method. It was observed that the stability of a phosphodiester linkage is dependent on the surrounding sequences of the phosphodiester linkage at high temperatures. The fact indicates that some weak interactions, such as hydrophobic interaction, might be effective within the oligonucleotides at high temperatures.