イシダ マリ   ISHIDA Mari   石田　万里    所属   広島修道大学  健康科学部    職種   教授
言語種別	英語
発行・発表の年月	2025/03
形態種別	学術論文
査読	査読有り
標題	Aged Garlic Extract Attenuates CaCl2-Induced Abdominal Aortic Aneurysm Formation by Inhibiting Matrix Metalloproteinase 9 Expression in Macrophages.
執筆形態	共著
掲載誌名	Mol Nutr Food Res.
掲載区分	国外
巻・号・頁	e70028
著者・共著者	Karasaki K, Ishida M, Kokubo H, Sakai C, Kobayashi Y, Yoshizumi M.
概要	Abdominal aortic aneurysm (AAA) is a local enlargement of the abdominal aorta with the risk of its fatal rupture. With lack of established medical treatments reducing the AAA growth, the development of treatment strategies for AAA is warranted. In this study, we examined whether aged garlic extract (AGE), which reportedly has vasoprotective effects, attenuates AAA formation in an animal model. The present findings indicate that AGE diminishes AAA formation by mitigating tissue destruction, highlighting the potential cardiovascular benefits of AGE intake.