カワムラ　クニオ   KAWAMURA Kunio   川村　邦男    所属   広島修道大学  人間環境学部    職種   教授
言語種別	英語
発行・発表の年月	2009/07
形態種別	学術論文
査読	査読有り
標題	Effect of condensation agents and minerals for oligopeptide formation under mild and hydrothermal conditions in related to chemical evolution of proteins
執筆形態	共著
掲載誌名	Advances in Space Research
掲載区分	国外
巻・号・頁	44(2),pp.267-275
担当範囲	Corresponding author
著者・共著者	◎Kunio Kawamura, Hitoshi Takeya, Takao Kushibe
概要	The role of condensation agents and minerals for oligopeptide formation was inspected to see whether minerals possess catalytic activ- ity under mild and hydrothermal conditions. Under mild conditions, oligopeptide formation from negatively charged amino acids (Asp and Glu) using different minerals and the elongation of alanine oligopeptides ((Ala)2–(Ala)5) were attempted using apatite minerals. Notable influence of minerals was not detected for the oligo(Asp) formation. The formation of oligo(Glu) was less efficient in the presence of carbonyldiimidazole. The elongation from (Ala)3, (Ala)4, and (Ala)5 and the formation of diketopiperazine from (Ala)2 proceeded immediately in the presence of EDC in the meantime of the sample preparations. These facts suggest that the activation of the reactant amino acids or peptides immediately occurs.