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学歴
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著書・論文歴
学会発表
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(最終更新日:2024-12-11 16:01:04)
イシダ マリ
ISHIDA Mari
石田 万里
所属
広島修道大学 健康科学部
職種
教授
■
現在の専門分野
●専門分野
●キーワード
●主な研究テーマ
●共同研究・研究相談が可能な内容
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学歴
1.
1991/04~1994/03
広島大学 大学院 医学系研究科 内科系専攻 博士課程修了 博士(医学) 第1221号
2.
~1987/03
広島大学 医学部 医学科 卒業
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資格・免許
1.
1987/05
医師免許
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所属学会
1.
1987/10~
日本内科学会
2.
1988/04~
日本循環器学会
3.
1988/04~
∟
Fellow of Japanese Circulation Society (FJCS)
4.
1988/04~
∟
各種委員会委員
5.
1988/04~
∟
循環器専門医
6.
1988/04~
∟
中国支部評議員
7.
1990/07~
日本高血圧学会
8.
2018/01~
∟
各種委員会委員および委員長
9.
2018/01~
∟
特別正会員
10.
2022~
∟
理事
11.
1995~
American Heart Association
12.
2006/04~
日本動脈硬化学会
13.
2017/06~
日本脈管学会
14.
2022/04~
日本血管不全学会
5件表示
全件表示(14件)
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職歴
1.
1987/06~1989/03
静岡県立総合病院 研修医
2.
1989/04~1990/03
静岡県立総合病院 医員(静岡県技術吏員)
3.
1990/04~1991/03
呉記念病院 医師
4.
1990/04~1991/03
広島大学 第一内科 研究生
5.
1991/04~1994/03
康成病院 医師(常勤)
6.
1994/06~1998/09
University of Washington (ワシントン州シアトル) 医学部 上級研究員
7.
1998/10~2002/09
広島大学 医学部附属病院 医員
8.
2002/10~2006/02
広島大学 原爆放射線医科学研究所 助手
9.
2006/03~2006/12
広島大学 原爆放射線医科学研究所 助手
10.
2007/01~2012/05
広島大学大学院 医歯薬学総合研究科 講師
11.
2012/04~2017/03
広島大学大学院 医歯薬保健学研究院 講師
12.
2017/04~2018/01
広島大学大学院 医歯薬保健学研究科 講師
13.
2018/04~2019/03
広島大学大学院 医歯薬保健学研究科 准教授
14.
2019/04~2024/09
広島大学大学院 医系科学研究科 准教授
5件表示
全件表示(14件)
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著書・論文歴
1.
著書
女性の高血圧 (共著) 2020
2.
著書
CTにおける被ばくの生物学的影響 (共著) 2018
3.
著書
血圧調節系と高血圧成因論に関する現状と展望:心血管系による血圧調節 (共著) 2018
4.
著書
放射線治療による心血管合併症について教えてください (共著) 2018
5.
著書
AII受容体拮抗薬の大規模臨床試験に学ぶもの (共著) 2000
6.
論文
Cigarette Smoking and Atherosclerotic Cardiovascular Disease. (共著) 2024/04
7.
論文
Mitochondrial DNA is a key driver in cigarette smoke extract-induced IL-6 expression. (共著) 2024/04
8.
論文
A possible role for proinflammatory activation via cGAS-STING pathway in atherosclerosis induced by accumulation of DNA double-strand breaks. (共著) 2023/04
9.
論文
Angiotensin II Type 1 Receptor Blocker Prevents Abdominal Aortic Aneurysm Progression in Osteoprotegerin-Deficient Mice via Upregulation of Angiotensin (1-7). (共著) 2023/04
10.
論文
Cigarette smoke induces mitochondrial DNA damage and activates cGAS-STING pathway -Application to a biomarker for atherosclerosis. (共著) 2023/04
11.
論文
Factors Influencing Acceptance of the Chairperson Position at Annual Scientific Meetings of the Japanese Circulation Society– A Questionnaire Survey in Chugoku District. (共著) 2023/04
12.
論文
Role of DNA damage in the pathogenesis of atherosclerosis. (共著) 2023/04
13.
論文
The time trend of information seeking behavior about salt reduction using Google Trends: infodemiological study in Japan. (共著) 2023/04
14.
論文
A Combination of Iohexol Treatment and Ionizing Radiation Exposure Enhances Kidney Injury in Contrast-Induced Nephropathy by Increasing DNA Damage. (共著) 2022/04
15.
論文
DNA Damage Induced by Radiation Exposure from Cardiac Catheterization. (共著) 2022/04
16.
論文
Hospitalizations for cardiovascular diseases during the early stage of the COVID-19 pandemic in Japan. (共著) 2022/04
17.
論文
How to deal with hypertension in the COVID-19 era-the impact "ON" and "OF" hypertension. (単著) 2022/04
18.
論文
Impact of Tweeting Summaries by the Japanese Circulation Society Official Account on Article Viewership- Pilot Trial. (共著) 2022/04
19.
論文
Cardiology Department Policy in Japan After Coronavirus Disease-2019 (COVID-19) ― Descriptive Summary of 2nd Nationwide Survey by the Japanese Circulation Society ― (共著) 2021/04
20.
論文
Cardiology Department Practices in the First Wave of the Coronavirus Disease Pandemic ― A Nationwide Survey in Japan by the Japanese Circulation Society ― (共著) 2021/04
21.
論文
Current Diversity Issues in Cardiovascular Workplaces in the Chugoku District- Results From 2 Questionnaire Surveys. (共著) 2021/04
22.
論文
Evaluating Individual Radiosensitivity for the Prediction of Acute Toxicities of Chemoradiotherapy in Esophageal Cancer Patients. (共著) 2021/04
23.
論文
New Vision, Mission, and Values of the Japanese Circulation Society. (共著) 2021/04
24.
論文
Relationship Between Official Twitter Ambassadors and the Number of Retweets in the Annual Congress -“Tweet the Meeting”-. (共著) 2021/04
25.
論文
S-1-Propenylcysteine promotes IL-10-induced M2c macrophage polarization through prolonged activation of IL-10R/STAT3 signaling. (共著) 2021/04
26.
論文
Smad4 regulates the nuclear translocation of Nkx2-5 in cardiac differentiation. (共著) 2021/04
27.
論文
Biological Effects of Low-Dose Chest CT on Chromosomal DNA. (共著) 2020/04
28.
論文
Coronavirus Disease 2019 (COVID-19) Information for Cardiologists- Systematic Literature Review and Additional Analysis. (共著) 2020/04
29.
論文
Disruption of Osteoprotegerin has complex effects on medial destruction and adventitial fibrosis during mouse abdominal aortic aneurysm formation. (共著) 2020/04
30.
論文
Potential Role of Twitter at an Annual Congress in Japan- Narrative Literature Review of “Tweet the Meeting” (共著) 2020/04
31.
論文
Two-Year Experience in "Tweeting the Meeting" During the Scientific Sessions - Rapid Report From the Japanese Circulation Society – (共著) 2020/04
32.
論文
DNA Damage and Senescence-Associated Inflammation in Cardiovascular Disease. (共著) 2019/04
33.
論文
Elevated Plasma Renin Activity Caused by Accelerated-malignant Hypertension in a Patient with Aldosterone-producing Adenoma Complicated with Renal Insufficiency. (共著) 2019/04
34.
論文
Genetic Prediction of Atherosclerosis - Significance of Polymorphisms in Bone Morphogenetic Protein Signaling Molecule Genes. (単著) 2019/04
35.
論文
JSH Statement: Asahikawa declaration in promotion of diversity by the Japanese society of hypertension-the JSH Asahikawa declaration. (共著) 2019/04
36.
論文
Chromosomal Abnormalities in Human Lymphocytes after Computed Tomography Scan Procedure. (共著) 2018/04
37.
論文
XRCC3 polymorphism is associated with hypertension-induced left ventricular hypertrophy. (共著) 2018/04
38.
論文
Fish oil omega-3 polyunsaturated fatty acids attenuate oxidative stress-induced DNA damage in vascular endothelial cells. (単著) 2017/04
39.
論文
Smoking Cessation Reverses DNA Double-strand Breaks in Human Mononuclear Cells. (共著) 2017/04
40.
論文
The ATR-Chk1 pathway plays a role in the generation of centrosome aberrations induced by Rad51C dysfunction. (共著) 2009/04
41.
論文
Nifedipine interferes with migration of vascular smooth muscle cells via inhibition of Pyk2-Src axis. (共著) 2006/04
42.
論文
Haploinsufficiency of Rad51B Causes Centrosome Fragmentation and Aneuploidy in Human Cells. (共著) 2005/04
43.
論文
Role of the JNK pathway in thrombin-induced ICAM-1 expression in endothelial cells. (共著) 2005/04
44.
論文
Matrix metalloproteinase-9 contributes to human atrial remodeling during atrial fibrillation. (共著) 2004/04
45.
論文
XRCC3 deficiency results in a defect in recombination and increased endoreduplication in human cells. (共著) 2004/04
46.
論文
Mnk1 is required for angiotensin II-induced protein synthesis in vascular smooth muscle cells. (共著) 2003/04
47.
論文
Apoptosis is not increased in myocardium overexpressing type 2 angiotensin II receptor in transgenic mice. (共著) 2001/04
48.
論文
Angiotensin II induces transactivation of two different populations of the platelet-derived growth factor beta receptor. Key role for the p66 adaptor protein Shc. (共著) 2000/04
49.
論文
The third cytoplasmic loop of the angiotensin II type 1 receptor exerts differential effects on extracellular signal-regulated kinase (ERK1/ERK2) and apoptosis via Ras- and Rap1-dependent pathways. (共著) 2000/04
50.
論文
Agonist-stimulated cytoskeletal reorganization and signal transduction at focal adhesions in vascular smooth muscle cells require c-Src. (共著) 1999/04
51.
論文
Activation of extracellular signal-regulated kinases (ERK1/2) by angiotensin II is dependent on c-Src in vascular smooth muscle cells. (共著) 1998/04
52.
論文
Angiotensin II stimulates p21-activated kinase in vascular smooth muscle cells: role in activation of JNK. (共著) 1998/04
53.
論文
p38 Kinase is a negative regulator of angiotensin II signal transduction in vascular smooth muscle cells: effects on Na+/H+ exchange and ERK1/2. (共著) 1998/04
54.
論文
Effects of insulin on calcium metabolism and platelet aggregation. Hypertension, (共著) 1996/04
55.
論文
Angiotensin II activates pp60c-src in vascular smooth muscle cells. (共著) 1995/04
56.
論文
Angiotensin II stimulates tyrosine phosphorylation of phospholipase C-gamma-associated proteins. Characterization of a c-Src-dependent 97-kD protein in vascular smooth muscle cells. (共著) 1995/04
57.
論文
Lack of increase in platelet Ca2+ and Na+ in deoxycorticosterone acetate-salt hypertensive rats. (共著) 1994/04
58.
論文
Platelet calcium handling in spontaneously hypertensive rats and in three strains of normotensive rats. (共著) 1993/04
59.
論文
Time-course of changes in intracellular cations and blood pressure with salt loading in patients with essential hypertension. (共著) 1991/04
5件表示
全件表示(59件)
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学会発表
1.
2024/05
Activation of Cgas-sting Axis By DNA Double-strand Breaks In Atherosclerosis: A Possible Link From DNA Damage To Infammation And Cell Senescence(Vascular Discovery 2024 Scientific Session)
2.
2024/05
Plasma mitochondria cell-free DNA is a possible biomarker for atherosclerosis(28th Asian Pacific Society of Cardiology Congress and the 15th Annual Emirates Cardiac Society Congress)
3.
2024/04
DNA 二本鎖切断蓄積はcGAS-STING-IRF3 を介して動脈硬化発症に関与する(第9回血管不全学会)
4.
2024/04
S-1-PROPENYLCYTEINE SUPPRESSES INFLAMMATION BY PROMOTING ANTI-INFLAMMATORY M2C MACROPHAGE POLARIZATION THROUGH PROLONGED ACTIVATION OF IL-10 RECEPTOR/STAT3 SIGNALING(International Garlic Symposium 2024)
5.
2024/04
Vascular Quest: Exploring Endothelial Cell Research from DNA Damage to Uncharted Realms of Vasculature and Beyond(第9回血管不全学会)
6.
2024/03
Role of DNA damage accumulation in cellular senescence and inflammation linked to atherosclerosis(第88回日本循環器学会学術集会)
7.
2024/02
ACE2-Angiotensin (1-7)-Mas receptor軸を介したAngiotensin II type 1 receptor blockerのAAA進行抑制作用(第53回日本心脈管作動物質学会年会)
8.
2024/02
DNA損傷の蓄積が心筋梗塞後の心臓リモデリングに及ぼす影響‐M2マクロファージの役割(第53回心脈管作動物質学会)
9.
2024/02
DNA二本鎖切断蓄積による動脈硬化発症メカニズムの探索(第53回心脈管作動物質学会)
10.
2024/02
タバコ煙による炎症惹起におけるミトコンドリアDNAの役割(第53回心脈管作動物質学会)
11.
2023/12
DNA damage-induced activation of cGAS-STING mediates inflammation and cellular senescence. BCVR2023(日本循環器学会)
12.
2023/12
DNA二本鎖切断蓄積はcGAS-STING経路を介して血管平滑筋細胞の炎症と細胞老化を誘導する(第46回日本分子生物学会年会)
13.
2023/11
DNA損傷応答の異常が心筋梗塞後の心臓リモデリングに及ぼす影響-マクロファージの動態における検討(第123回日本循環器学会中国地方会)
14.
2023/10
タバコ煙による炎症惹起とミトコンドリアDNAの関係(第129回日本内科学会中国地方会)
15.
2023/10
熟成ニンニク抽出液によるCaCl2誘導性マウス腹部大動脈瘤形成の減弱(第64回日本脈管学会学術総会)
16.
2023/09
CaCl2誘導性マウス腹部大動脈瘤モデルに対する熟成ニンニク抽出液摂食の影響 Effects of aged garlic extract intake on CaCl2-induced abdominal aortic aneurysms in mice(第45回日本高血圧学会総会)
17.
2023/09
タバコ煙による炎症惹起とミトコンドリアDNAの関係
18.
2023/09
動脈硬化発症におけるDNA二本鎖切断の役割 Possible Role of DNA Double-Strand Breaks in Atherosclerosis(第45回日本高血圧学会総会)
19.
2023/07
DNA二本鎖切断蓄積はcGAS-STING経路を介して血管平滑筋細胞の炎症を惹起する(第55回日本動脈硬化学会総会・学術集会)
20.
2023/07
タバコ煙によるミトコンドリアDNA損傷の誘発とcGAS-STING経路の活性化:動脈硬化のバイオマーカーへの応用(第55回日本動脈硬化学会総会・学術集会)
21.
2023/03
Cigarette Smoke Induces Mitochondrial DNA Damage and Activates Innate Immunity in Human Endothelial Cells -Application to a Biomarker for Atherosclerosis
22.
2023/02
Cigarette Smoke Extract induces DNA damage and accelerates cellular senescence in human endothelial cells(The 7th International Symposium of the Network-type Joint Usage-Research Center for Radiation Disaster Medical Science)
23.
2023/02
Roles of DNA damage accumulation in the initiation and progression of atherosclerosis(The 7th International Symposium of the Network-type Joint Usage/Research Center for Radiation Disaster Medical Science)
24.
2022/11
Role of DNA double-strand breaks in the initiation and progression of atherosclerosis(英)DNA二本鎖切断蓄積による動脈硬化進展メカニズムの探索(日)(第45回日本分子生物学会年会)
25.
2022/10
Cigarette Smoke Extract Induces DNA Damage and Triggers an Innate Immune Response(ISH2022)
26.
2022/10
Omega-3 fatty acids attenuate oxidative stress-induced DNA damage through Nrf-2 in vascular endothelial cells(ISH2022)
27.
2022/10
Polymorphism of DNA Repair Gene is Associated with Hypertension-induced Left Ventricular Hypertrophy – Role of DNA Damage and Cell Senescence(ISH2022)
28.
2022/10
Preventive effect of Angiotensin II type 1 receptor blocker against AAA progression in Opg-KO mice via up-regulation of Angiotensin (1-7)(ISH2022)
29.
2022/10
自律神経と血圧・循環調節(第75回日本自律神経学会総会)
30.
2022/08
DNA damage induced by radiation exposure from cardiac catheterization - an analysis in patients and operators(ESC Congress 2022)
31.
2022/06
循環器医療の魅力を探る:ダイバーシティとキャリアプラン(第133回日本循環器学会近畿地方会)
32.
2022/05
DNA損傷を基盤とする動脈硬化発症のメカニズム(第120回日本循環器学会中国・四国合同地方会)
33.
2022/05
喫煙による炎症惹起機構―血管内皮細胞における検討―(第120回日本循環器学会中国・四国合同地方会)
34.
2022/03
Cigarette Smoke Extract Induces Nuclear and Mitochondrial DNA Damage and Triggers an Innate Immune Response(第86回日本循環器学会学術集会)
35.
2022/03
Cigarette smoke-induced nuclear and mitochondrial DNA damage(第99回日本生理学会大会)
36.
2022/03
Current Diversity Issues in Cardiovascular Workplace in Chugoku District: Results from Two Questionnaire Surveys(第86回日本循環器学会学術集会)
37.
2022/03
“Angiotensin II type 1 receptor blocker prevents the development of AAA in Opg-KO mice via increase of Angiotensin (1-7).”(第86回日本循環器学会学術集会)
38.
2021/11
DNA Damage Promotes Atherosclerosis by Enhancing Inflammatory Responses via the DNA Sensing cGAS-Sting Pathway(AHA Scientific Sessions 2021)
39.
2021/11
Importance of mitochondrial DNA damage in cigarette smoke extract-induced activation of innate immune system(AHA Scientific Sessions 2021)
40.
2021/10
Accumulation of DNA damage promotes atherosclerosis by provoking inflammatory responses via cGAS-STING activation(The 19th International Symposium on Atherosclerosis)
41.
2021/10
タバコ煙抽出物が血管内皮細胞に炎症を引き起こすメカニズムの探索―核とミトコンドリアDNA損傷の観点から(第62回日本脈管学会総会)
42.
2021/10
タバコ煙抽出物の内皮細胞に及ぼす影響―核とミトコンドリアDNA損傷の観点から(第43回日本高血圧学会総会)
43.
2021/10
妊娠高血圧症候群の病態生理(第43回日本高血圧学会総会)
44.
2021/10
脈管系をどう守る?―DNA損傷・細胞老化の側面から(第62回日本脈管学会総会)
45.
2021/09
Cigarette smoke extract-induced nuclear and mitochondrial DNA damage evokes an innate immune response(第5回日本循環器学会基礎研究フォーラム)
46.
2021/04
Cigarette smoke extract induces DNA damage and accelerates cellular senescence in human endothelial cells(Joint Meeting ESH-ISH)
47.
2021/02
Cigarette smoke-induced nuclear and mitochondrial DNA damage evokes an innate immune response.(The 5th International Symposium of the Network-type Joint Usage/Research Center for Radiation Disaster Medical Science)
48.
2021/02
Impaired DNA damage response promotes atherosclerosis by enhancing cellular senescence and proinflammatory activation.(The 5th International Symposium of the Network-type Joint Usage/Research Center for Radiation Disaster Medical Science)
49.
2020/12
Cigarette smoke extract induces the release of nuclear and mitochondrial DNA into the cytosol and chronic inflammation via activation of the cGAS-STING pathway.(第43回日本分子生物学会年会)
50.
2020/12
Role of XRCC3 polymorphism in hypertension-induced left ventricular hypertrophy.
51.
2020/10
“ARBはTrail- JNK- Mmp-9 経路活性化を伴うAAA重症化を抑制する”(第61回日本脈管学会総会)
52.
2020/08
Impaired DNA damage response promotes atherosclerosis by enhancning senescence and proinflammatory activation.(ESC congress 2020)
53.
2020/08
Role of Impaired DNA Damage Response in the Initiation and Progression of Atherosclerosis. The 84th Annual Scientific Meeting of the Japanese Circulation Society.(日本循環器学会)
54.
2020/03
タバコ煙抽出物の内皮細胞に及ぼす影響ーDNA損傷・老化の観点から Effects of cigarette smoke extract on endothelial cells-From the viewpoint of DNA damage and cellular senescence(第97回日本生理学会大会)
5件表示
全件表示(54件)
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受賞学術賞
1.
1991/06
Travel Awards for Young Investigators, 5th Eouropean Meeting on Hypertension, Eouropean Society of H
2.
2003/06
財団法人 地域医学研究基金 高血圧と動脈硬化研究会部会 優秀賞
3.
2005/08
武田科学振興財団報彰基金研究奨励賞
4.
2023/07
第55回日本動脈硬化学会総会・学術集会 優秀賞
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改善への取り組み
前年度の点検・評価項目